Saturday, August 18, 2018

HPLC-13

How CAD detector works?

The steps involved in CAD-Charged Aerosol Detector :
  • The mobile phase from the column enters into CAD
  • Pneumatic nebulization of mobile phase creates aerosol droplets
  • Conditioning of aerosol occurs to remove the large droplets
  • Evaporation of solvent from the formed aerosol leads to dried particles
  • An Ion jet induces charge to the dried particles
  • An Ion trap is used to select the particles and remove the excess ions from them
  • The charge of those selected particles can be measured and detected by using Electromter
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